abstract：:Nicotinic acetylcholine receptors (nAChRs) are widely distributed in the central nervous system and have been implicated in multiple behavioral paradigms and pathological conditions. Nicotinic therapeutic interventions require an extensive characterization of native nAChRs including mapping of their distribution and f...

journal_title：Progress in brain research

authors： Alkondon M,Albuquerque EX

更新日期：2004-01-01 00:00:00

abstract：:An unresolved issue in visual motion perception is how distinct are the processes underlying 'first-order' and 'second-order' motion. The former is defined by spatio-temporal variations of luminance and the latter by spatio-temporal variations in other image attributes such as contrast or depth, for example. Using neu...

journal_title：Progress in brain research

authors： Vaina LM,Soloviev S

更新日期：2004-01-01 00:00:00

abstract：:The two roles in awareness most often suggested for the cerebellum are (i) keeping the details of motor skills away from forebrain computation, and (ii) signaling to the forebrain when a sensory event is not predictable from prior motor commands. However, it is unclear how current models of the cerebellum could carry ...

journal_title：Progress in brain research

authors： Dean P,Porrill J,Stone JV

更新日期：2004-01-01 00:00:00

abstract：:Orienting one's gaze towards a peripheral target is usually composed of a hypometric primary saccade followed by a secondary 'corrective saccade' triggered automatically (without conscious perception) by the retinal error at the end of the primary saccade and characterised by a short latency. Due to visual suppression...

journal_title：Progress in brain research

authors： Prablanc C,Desmurget M,Gréa H

更新日期：2003-01-01 00:00:00

abstract：:The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscle...

journal_title：Progress in brain research

authors： Shefchyk SJ

更新日期：2002-01-01 00:00:00

abstract：:The interactions of the dendritically released neuropeptides vasopressin and oxytocin with co-released neuroactive substances such as opioids and nitric oxide are reviewed. Endogenous opioids regulate magnocellular neurons at the level of the supraoptic nucleus and the relationship of dendritically released peptides a...

journal_title：Progress in brain research

authors： Ludwig M,Sabatier N,Dayanithi G,Russell JA,Leng G

更新日期：2002-01-01 00:00:00

abstract：:The hypothalamic-neurohypophysial system undergoes dramatic morphological plasticity in response to physiological activation during parturition/lactation and dehydration, including somatic swelling, decreased glial coverage and increased synaptic innervation of the magnocellular neuroendocrine cells. Recent in-vitro e...

journal_title：Progress in brain research

authors： Tasker JG,Di S,Boudaba C

更新日期：2002-01-01 00:00:00

abstract：:VLBW infants are at risk of lesions including intraventricular haemorrhage and periventricular leucomalacia. Those with normal IQ still present with reading difficulties. Oculomotor performance was assessed on 14 VLBWs (IQ > 85) and 15 full-term age-matched controls. Anti-saccade errors were significantly higher for t...

journal_title：Progress in brain research

authors： Newsham D,Knox PC

更新日期：2002-01-01 00:00:00

abstract：:In recent years the scientific community has come to appreciate that the early cortical representations for visually guided arm movements are probably coded in a visual frame, i.e. relative to retinal landmarks. While this scheme accounts for many behavioral and neurophysiological observations, it also poses certain p...

journal_title：Progress in brain research

authors： Henriques DY,Medendorp WP,Khan AZ,Crawford JD

更新日期：2002-01-01 00:00:00

abstract：:When we move our eyes around in real-world scenes, we typically have several peripheral previews of an object before we direct our eyes straight at the object. Numerous studies on transsaccadic memory have investigated whether there is any evidence for the integration of peripheral object information acquired presacca...

journal_title：Progress in brain research

authors： De Graef P,Verfaillie K

更新日期：2002-01-01 00:00:00

abstract：:Quantitative models of the oculomotor plant and control of the saccadic eye movement system are presented in this chapter. Oculomotor plant models described here are linear, including a second-order model by Westheimer (1954), Bahill et al. (1980) and Enderle et al. (2000). The model of the saccade generator is initia...

journal_title：Progress in brain research

authors： Enderle JD

更新日期：2002-01-01 00:00:00

abstract：:The results from the language studies taken as a whole point to different developmental time courses and developmental vulnerabilities of aspects of grammatical and semantic/lexical processing. They thus provide support for conceptions of language that distinguish these subprocesses within language. Similarly, followi...

journal_title：Progress in brain research

authors： Neville H,Bavelier D

更新日期：2002-01-01 00:00:00

abstract：:In the "Histology of the Nervous System" (Histologie, Spanish edition, 1899, 1904; French translation, 1909, 1911; all citations are from the American translation, 1995) Cajal did not only describe the origins and central pathways of cranial nerves but his detailed observations led him to numerous conclusions about th...

journal_title：Progress in brain research

authors： Schwarzacher SW

更新日期：2002-01-01 00:00:00

abstract：:This overview highlights the presentations made by several authors, with sidelights commentaries on the topics covered in this session. The Neurotropic hypothesis, formulated by Cajal more than one century ago, has been one of the fundamental tenets of modern Neuroscience. Research work is unveiling highly complex mol...

journal_title：Progress in brain research

authors： Valverde F

更新日期：2002-01-01 00:00:00

abstract：:Chronic epilepsy, as a consequence of status epilepticus, has been studied in animal models in order to analyze the cellular mechanisms responsible for the subsequent occurrence of spontaneous seizures. Status epilepticus, induced by either kainic acid or pilocarpine or by prolonged electrical stimulation, causes a ch...

journal_title：Progress in brain research

authors： Dudek FE,Hellier JL,Williams PA,Ferraro DJ,Staley KJ

更新日期：2002-01-01 00:00:00

abstract：:Children with epilepsy are known to have high rates of mental health problems. The role of seizures in the development of these problems is not known primarily because of difficulties in separating the effects of seizures from the three other potential causal factors: (a) poor child and family response to the conditio...

journal_title：Progress in brain research

authors： Austin JK,Dunn DW

更新日期：2002-01-01 00:00:00

abstract：:Selective neuronal loss following status epilepticus was first described just under 100 years ago. The acute pathology following status epilepticus was shown to be 'ischemic cell change' and was assumed to arise through hypoxia/ischemia. Less than 30 years ago it was proposed, from experiments in primates, that the se...

journal_title：Progress in brain research

authors： Meldrum BS

更新日期：2002-01-01 00:00:00

abstract：:Studies in vitro and in other disease states where excitotoxicity is believed to be important have demonstrated that mitochondrial function is a critical determinant of cell death, reflecting key roles in intracellular calcium homeostasis, energy production and oxidative stress. Central to this is the process of mitoc...

journal_title：Progress in brain research

authors： Cock HR

更新日期：2002-01-01 00:00:00

abstract：:We studied visually guided behavior and the visual response properties of single auditory cortex (A1) neurons in neonatally operated hamsters with surgically induced, permanent, ectopic retinal projections to auditory thalamic nuclei and to visual thalamic nuclei which normally receive little direct retinal input. The...

journal_title：Progress in brain research

authors： Ptito M,Giguère JF,Boire D,Frost DO,Casanova C

更新日期：2001-01-01 00:00:00

abstract：:Selective attention is an important aspect of brain function that we need in coping with the immense and constant barrage of sensory information. One model of attention (Feature Integration Theory) that suggests an early selection of spatial locations of objects via an attentional spotlight would also solve the 'bindi...

journal_title：Progress in brain research

authors： Vidyasagar TR

更新日期：2001-01-01 00:00:00

abstract：:Although visually responsive neurons predominate in the deep layers of the superior colliculus (SC), the majority of them also receive sensory inputs from nonvisual sources (i.e. auditory and/or somatosensory). Most of these 'multisensory' neurons are able to synthesize their cross-modal inputs and, as a consequence, ...

journal_title：Progress in brain research

authors： Stein BE,Jiang W,Wallace MT,Stanford TR

更新日期：2001-01-01 00:00:00

abstract：:Activated microglia release a number of substances, the specific cocktail released depending on the stimulus. Many of the substances released by microglia also serve to activate them, suggesting the presence of a number of autocrine/paracrine loops. Because of the low density of microglia present in the normal brain, ...

journal_title：Progress in brain research

authors： Pocock JM,Liddle AC

更新日期：2001-01-01 00:00:00

abstract：:Puerperal psychosis, an episode of mania or psychosis precipitated by childbirth follows approximately one in 1000 deliveries. The evidence of clinical, outcome and genetic studies supports the hypothesis that the majority of puerperal psychotic episodes are manifestations of an affective disorder diathesis with a pue...

journal_title：Progress in brain research

authors： Jones I,Lendon C,Coyle N,Robertson E,Brockington I,Craddock N

更新日期：2001-01-01 00:00:00

abstract：:Follicular development and ovulation are strongly inhibited during lactation. Administration of a high dose of estrogen induces luteinizing hormone (LH) surges in ovariectomized lactating rats, suggesting that brain mechanisms regulating cyclic LH release remain intact in lactating mothers. On the other hand, tonic LH...

journal_title：Progress in brain research

authors： Tsukamura H,Maeda K

更新日期：2001-01-01 00:00:00

abstract：:Recordings of spinal INs during a flexion/extension wrist task with an instructed delay period have shown directly that many spinal neurons modulate their rate during the preparatory period soon after a visual cue. The onset time and the relation between the delay period activity of spinal INs and the ensuing movement...

journal_title：Progress in brain research

authors： Prut Y,Perlmutter SI,Fetz EE

更新日期：2001-01-01 00:00:00

abstract：:Neuroimaging studies of major depression have identified neurophysiological abnormalities in multiple areas of the prefrontal cortex (PFC), the amygdala, and related parts of the striatum and thalamus. Some of these abnormalities are mood state-dependent, and appear in regions where cerebral blood flow (CBF) increases...

journal_title：Progress in brain research

authors： Drevets WC

更新日期：2000-01-01 00:00:00

abstract：:The Tibetan Buddhist classification of mind, its divisions and the system of meditation practices aimed at achieving ideal states of being are a complex presentation of psychological, behavioral and spiritual concepts and processes that demand thorough understanding before assessing their value and outcome (Yeshe, 199...

journal_title：Progress in brain research

authors： Rapgay L,Rinpoche VL,Jessum R

更新日期：2000-01-01 00:00:00

abstract：:Experimental investigations of the lumbar sympathetic outflow to skin, skeletal muscle and viscera and the thoracic sympathetic outflow to the head and neck have shown that each target organ and tissue is supplied by one or two separate pathways which consists of sets of pre- and postganglionic neurons with distinct p...

journal_title：Progress in brain research

authors： Jänig W,Häbler HJ

更新日期：2000-01-01 00:00:00

abstract：:The major point of this chapter is that there is evidence to support the idea that cervical headache might not only result from injured somatic structures in the neck but also occur because of interactions with visceral organs. The complex arrangement of convergent inputs from somatic and visceral afferent fibers and ...

journal_title：Progress in brain research

authors： Foreman RD

更新日期：2000-01-01 00:00:00

abstract：:The effects of endogenous metabolites of the neuropeptide vasopressin (VP) in behavioural tests led to the hypothesis that VP metabolites have a more selective function than VP. In contrast to VP, no peripheral effects have been found thus far with VP metabolites and their function seems to be associated with memory-r...

journal_title：Progress in brain research

authors： Reijmers LG,van Ree JM,Spruijt BM,Burbach JP,De Wied D

更新日期：1998-01-01 00:00:00

abstract：:Vasopressin (VP) is one of the principal neurotransmitters of the suprachiasmatic nucleus (SCN). By means of anatomical, physiological and electrophysiological techniques we have demonstrated that VP containing pathways from the SCN serve to affect neuroendocrine and 'autonomic' neurons in the paraventricular nucleus....

journal_title：Progress in brain research

authors： Buijs RM,Hermes MH,Kalsbeek A

更新日期：1998-01-01 00:00:00

abstract：:In addition to its peripheral secretion from the neurohypophysis, the neuropeptide vasopressin (VP) is released within the mammalian brain from probably all parts of the neuronal membrane. In particular the development of brain microdialysis in vivo together with blood microdialysis or blood sampling provides the adva...

journal_title：Progress in brain research

authors： Landgraf R,Wotjak CT,Neumann ID,Engelmann M

更新日期：1998-01-01 00:00:00

abstract：:High affinity binding sites for vasopressin (VP) are widely distributed within the rat brain and spinal cord. Since their presence is associated with neuronal sensitivity to VP application, their anatomical distribution maps structures which could be activated by endogenous VP. Interestingly, marked species-related di...

journal_title：Progress in brain research

authors： Tribollet E,Arsenijevic Y,Barberis C

更新日期：1998-01-01 00:00:00

abstract：:Nitric oxide (NO) is widespread in the nervous system and is thought to play a role in a variety of different neuronal functions, including learning and memory (see other chapters, this volume). A number of behavioral studies have indicated that NO is involved in several types of learning such as motor learning (Yanag...

journal_title：Progress in brain research

authors： Hawkins RD,Son H,Arancio O

更新日期：1998-01-01 00:00:00

abstract：:Neuronal nitric oxide synthase (nNOS) participate in a variety of physiologic and pathologic processes in the nervous system. nNOS was originally felt to be a constitutively expressed enzyme, but recent observations suggest that its levels are dynamically controlled in response to neuronal development, plasticity and ...

journal_title：Progress in brain research

authors： Dawson TM,Sasaki M,Gonzalez-Zulueta M,Dawson VL

更新日期：1998-01-01 00:00:00

abstract：:1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e. amorphous plaques, n...

journal_title：Progress in brain research

authors： Swaab DF,Lucassen PJ,Salehi A,Scherder EJ,van Someren EJ,Verwer RW

更新日期：1998-01-01 00:00:00

abstract：:Neuronal activity increases synthesis of brain-derived neurotrophic factor (BDNF) mRNA in vivo and in vitro. We have investigated the pathways through which neuronal activity stimulated by kainic acid regulates BDNF mRNA levels in cultured hippocampal neurons and transgenic mice. Kainic acid induced the transcription ...

journal_title：Progress in brain research

authors： Castrén E,Berninger B,Leingärtner A,Lindholm D

更新日期：1998-01-01 00:00:00

abstract：:Motor control is defined as the process of restricting the output of the motor nervous system so that meaningful and coordinated behavior ensues. The high dimensionality of the computation underlying motor control is presented and a simplifying framework is outlined. Evidence that movements are performed non-continuou...

journal_title：Progress in brain research

authors： Welsh JP,Llinás R

更新日期：1997-01-01 00:00:00

abstract：:The success of axon regeneration in the adult mammalian brain depends on the presence of growth-permissive environmental conditions as well as on specific properties of the affected neurons. To investigate the relative contribution of extrinsic cues and intrinsic determinants to reparative processes we have investigat...

journal_title：Progress in brain research

authors： Rossi F,Bravin M,Buffo A,Fronte M,Savio T,Strata P

更新日期：1997-01-01 00:00:00

abstract：:The organization of key molecules at glutamatergic synapses in the rat cerebellar cortex as analyzed by high resolution immunocytochemical techniques using gold particles as markers. The distinct compartmentation of glutamate and glutamine was consistent with biochemical data indicating an active role of glia in the r...

journal_title：Progress in brain research

authors： Ottersen OP,Chaudhry FA,Danbolt NC,Laake JH,Nagelhus EA,Storm-Mathisen J,Torp R

更新日期：1997-01-01 00:00:00